The study aimed to examine associations of clinic and 24-h ABPM with all-cause and cardiovascular mortality in a large cohort of primary care patients referred for assessment of hypertension across Spain fro 223 primary care centers between 2004 and 2013 with follow up in 2019.FINDINGS:
During a median follow-up of 10 years, 7174 (12·1%) of 59 124 patients died, including 2361 (4·0%) from cardiovascular causes.
24-h systolic blood pressure from ABPM was more strongly associated with all-cause death than clinic systolic blood pressure.
Compared with the informativeness of clinic systolic blood pressure (100%), night-time systolic blood pressure was most informative about risk of all-cause death (591%) and cardiovascular death (604%).
Relative to blood pressure within the normal range, elevated all-cause mortality risks were observed for masked hypertension and sustained hypertension but not white-coat hypertension, and elevated cardiovascular mortality risks were observed for masked hypertension and sustained hypertension but not white-coat hypertension.
IMPORTANCE:
Ambulatory blood pressure monitoring, or ABPM) for 24 hours, provides much more information related to risk and future death than clinic blood pressures. Particularly, night-time blood pressure, was more informative about the risk of all-cause death and cardiovascular death than clinic blood pressure.
The new 24 hour ABPM patch used at the Kahn Center has made this testing very simple and comfortable.
