STUDY
The relationship between sleep pattern and coronary artery calcification (CAC) measured by non-contrast CT scans in the Swedish CArdioPulmonary bioImage Study (SCAPIS) pilot cohort was assessed. Participants aged 50–64 years were randomly recruited and underwent extensive examination including imaging and assessments of physical activity. 771 participants (47 % male, average age 58 years) were included in this analysis. Self-assessed sleep type was classified as extreme morning, moderate morning, intermediate, moderate evening, or extreme evening. 10-year risk of first-onset cardiovascular disease was estimated.
Significant CAC (a calcium score at least >10) was present in 29 % of the cohort. CAC prevalence increased from extreme morning to extreme evening type (22 %, 28 %, 29 %, 27 %, 41 % respectively).
In an assessment controlling for confounders, extreme evening chronotype was independently associated with increased CAC prevalence compared to extreme morning type (1.9X higher prevalence).
IMPLICATIONS
The study findings suggest sleep patterns may play an importantrole in atherosclerosis. If you are an extreme night owl perhaps consider rearranging your pattern, perhaps half an hour at a time earlier week after week, and follow the age old saying “early to bed, early to rise”.